Season Six Episode Guide


Episode #: 601
Air Date: 03.30.2021

As Brainiac lays close to death after trying to stop Lex, Supergirl and team soar in to save him, engaging in an epic battle with Gamenmae. After beating Leviathan, Supergirl turns her attention to Lex who has used the Obsidian platform to brainwash half the world to love him and follow him at all costs, no matter what horrible things he does. (The CW)

A Few Good Women

Episode #: 602
Air Date: 04.06.2021

As the stakes with Lex are raised higher than ever before, Lena must decide how far she is willing to go to stop her brother. Meanwhile, Supergirl and the team are faced with a challenge unlike anything they've ever dealt with before and it brings Alex to her breaking point. (The CW)

Phantom Menaces

Episode #: 603
Air Date: 04.13.2021

Supergirl makes a new ally. Lena and Lex battle for control of Luthor Corp. (The CW)

Lost Souls

Episode #: 604
Air Date: 04.20.2021

Supergirl finds an opportunity to escape from the Phantom Zone but it comes with some dangerous strings attached. Meanwhile, Lena joins the Super Friends on a mission but finds she disagrees with their plan of action against the Phantoms. (The CW)

Prom Night!

Episode #: 605
Air Date: 04.27.2021

Nia and Brainy attempt to save Supergirl from the Phantom Zone by time traveling back to Kara's home in 2009. While determined to secure the item needed to help Supergirl, Brainy is worried about keeping a low profile so as not to alter the future timeline. (The CW)

Prom Again!

Episode #: 606
Air Date: 05.04.2021

Young Kara experiences kryptonite for the first time, Nia and Brainy are trapped by invading aliens, and a young Cat Grant may be the reason Supergirl never gets out of the Phantom Zone. (The CW)

Fear Knot

Episode #: 607
Air Date: 05.11.2021

As the Super Friends brave the Phantom Zone to bring Supergirl home, each member of the team is confronted by visions of their worst fear. (The CW)

Welcome Back, Kara

Episode #: 608
Air Date: 08.24.2021

As Supergirl and Zor-El make their return to National City, they are determined to keep the Phantom Zone behind them and enjoy being superheroes together. Unfortunately, their overzealous efforts backfire, creating a whole new threat to National City. (The CW)

Dream Weaver

Episode #: 609
Air Date: 08.31.2021

Kelly meets Joey, a young orphaned alien boy, who is acting out in foster care because he fears there is something wrong with his brother Orlando, who is incarcerated. (The CW)

Still I Rise

Episode #: 610
Air Date: 09.07.2021

Supergirl intervenes when a building in the Heights that was set aside for low income housing is suddenly at risk to be sold to a major corporation. Supergirl recruits Orlando to help her win over the city, but things go awry when Nyxly shows up. (The CW)

Mxy in the Middle

Episode #: 611
Air Date: 09.14.2021

Supergirl and team must stop Nyxly from vanquishing a familiar face from Supergirl's past - Mr. Mxyzptlk. Mxy returns and explains Nyxly's dark history to the super team in the best way he knows how - in song form. Meanwhile, Lena visits her mother's birthplace in Ireland, eager to dig into her past but is shocked by the small town's icy reception towards her. (The CW)

Blind Spots

Episode #: 612
Air Date: 09.21.2021

Kelly is horrified when the Ormfell building implodes, injuring many in the community, including Joey. However, her horror quickly turns to frustration when she realizes that the hospital is overwhelmed, people are getting sicker, and no one is coming to help – including Supergirl who is busy fighting Nyxly. (The CW)

The Gauntlet

Episode #: 613
Air Date: 09.28.2021

Supergirl and team race Nyxly for control of a magical totem that controls courage. Supergirl and Nyxly battle and each get a piece of the totem but learn the first person to pass the test of courage will gain control of the entire thing. Meanwhile, Lena is still struggling to make sense of her newfound gift. (The CW)

Magical Thinking

Episode #: 614
Air Date: 10.05.2021

Lena is uncertain about using her magical abilities to help Supergirl retrieve the second totem from Nyxly. William struggles to write a story on the Super Friends that makes both the heroes and Andrea happy. (The CW)

Hope for Tomorrow

Episode #: 615
Air Date: 10.12.2021

Supergirl continues to fight Nyxly for the remaining totems but after Nyxly kidnaps William, Supergirl realizes she needs to take a more proactive stance to keep National City safe. Meanwhile, Alex faces the biggest challenge of her life. (The CW)

Nightmare in National City

Episode #: 616
Air Date: 10.19.2021

Kara lands her dream story for Catco but when the city is suddenly attacked by a nightmare monster at the same time as her interview, she is forced to take a serious look at her life and decide if she can continue to live as both Kara and Supergirl. As Dreamer takes the lead on the search for the Dream Totem, which can vanquish they nightmare monster in National City, she realizes she needs to ask her sister Mauve for help. (The CW)

I Believe In A Thing Called Love

Episode #: 617
Air Date: 10.26.2021

When Lex Luthor appears by Nyxly's side, Supergirl and team must deal with the emotional fallout of facing their two biggest foes at the same time. Alex makes plans for the perfect proposal to Kelly, but work keeps getting in the way. (The CW)

Truth or Consequences

Episode #: 618
Air Date: 11.02.2021

Supergirl is determined to keep everyone safe from Lex and Nyxly so she doubles down on patrol, especially as Alex and Kelly's bachelorette party is coming up. Alex is torn between duty and finally allowing herself the time to enjoy her new family. Brainy receives heartbreaking news, and William clashes with Andrea over her recent coverage of Lex. (The CW)

The Last Gauntlet

Episode #: 619
Air Date: 11.09.2021

In the penultimate buildup to the season finale, Supergirl and the super friends take drastic action after a loved one is kidnapped by Nyxly and Lex. An unlikely ally steps in to help the team. (The CW)


Episode #: 620
Air Date: 11.09.2021

Supergirl is joined by familiar faces from the past to help her stop Lex and Nyxly for good. Meanwhile, Alex and Kelly prepare to walk down the aisle. (The CW)